Chapter II


Malignant neoplasms

Malignant neoplasms of lymphoid, haematopoietic and related tissue

Note: The terms used in categories C82-C85 for non-Hodgkin's lymphomas are those of the Working Formulation, which attempted to find common ground among several major classification schemes. The terms used in these schemes are not given in the Tabular List but appear in the Alphabetical Index; exact equivalence with the terms appearing in the Tabular List is not always possible.
Includes: morphology codes M959-M994 with behaviour code /3
Excludes: secondary and unspecified neoplasm of lymph nodes ( C77.- )

C81 Hodgkin's disease
Includes: morphology codes M965-M966 with behaviour code /3
C81.0 Lymphocytic predominance
Lymphocytic-histiocytic predominance
C81.1 Nodular sclerosis
C81.2 Mixed cellularity
C81.3 Lymphocytic depletion
C81.7 Other Hodgkin's disease
C81.9 Hodgkin's disease, unspecified

C82 Follicular [nodular] non-Hodgkin's lymphoma
Includes: follicular non-Hodgkin's lymphoma with or without diffuse areas
morphology code M969 with behaviour code /3
C82.0 Small cleaved cell, follicular
C82.1 Mixed small cleaved and large cell, follicular
C82.2 Large cell, follicular
C82.7 Other types of follicular non-Hodgkin's lymphoma
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
Nodular non-Hodgkin's lymphoma NOS

C83 Diffuse non-Hodgkin's lymphoma
Includes: morphology codes M9593, M9595, M967-M968 with behaviour code /3
C83.0 Small cell (diffuse)
C83.1 Small cleaved cell (diffuse)
C83.2 Mixed small and large cell (diffuse)
C83.3 Large cell (diffuse)
Reticulum cell sarcoma
C83.4 Immunoblastic (diffuse)
C83.5 Lymphoblastic (diffuse)
C83.6 Undifferentiated (diffuse)
C83.7 Burkitt's tumour
C83.8 Other types of diffuse non-Hodgkin's lymphoma
#C83.80 Mantle cell lymphoma
#C83.81 Lymphoma of mucosa-associated lymphoid tissue [MALT]
#C83.88 Other types of diffuse non-Hodgkin's lymphoma
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified

C84 Peripheral and cutaneous T-cell lymphomas
Includes: morphology code M970 with behaviour code /3
C84.0 Mycosis fungoides
C84.1 Sézary's disease
C84.2 T-zone lymphoma
C84.3 Lymphoepithelioid lymphoma
Lennert's lymphoma
C84.4 Peripheral T-cell lymphoma
#C84.40 Anaplastic large cell lymphoma
#C84.41 Angiocentric lymphoma
#C84.42 Angioimmunoblastic lymphoma
#C84.43 Hepatosplenic T-cell lymphoma
#C84.48 Other peripheral T-cell lymphoma
#C84.49 Peripheral T-cell lymphoma, unspecified
C84.5 Other and unspecified T-cell lymphomas
Note: If T-cell lineage or involvement is mentioned in conjunction with a specific lymphoma, code to the more specific description.

C85 Other and unspecified types of non-Hodgkin's lymphoma
Includes: morphology codes M9590-M9592, M9594, M971 with behaviour code /3
C85.0 Lymphosarcoma
C85.1 B-cell lymphoma, unspecified
Note: If B-cell lineage or involvement is mentioned in conjunction with a specific lymphoma, code to the more specific description.
C85.7 Other specified types of non-Hodgkin's lymphoma
· reticuloendotheliosis
· reticulosis
C85.9 Non-Hodgkin's lymphoma, unspecified type
Lymphoma NOS
Malignant lymphoma NOS
Non-Hodgkin's lymphoma NOS

C88 Malignant immunoproliferative diseases
Includes: morphology code M976 with behaviour code /3
C88.0 Waldenström's macroglobulinaemia
C88.1 Alpha heavy chain disease
C88.2 Gamma heavy chain disease
Franklin's disease
C88.3 Immunoproliferative small intestinal disease
Mediterranean disease
C88.7 Other malignant immunoproliferative diseases
C88.9 Malignant immunoproliferative disease, unspecified
Immunoproliferative disease NOS

C90 Multiple myeloma and malignant plasma cell neoplasms
Includes: morphology codes M973, M9830 with behaviour code /3
C90.0 Multiple myeloma
Kahler's disease
Excludes: solitary myeloma ( C90.2)
C90.1 Plasma cell leukaemia
C90.2 Plasmacytoma, extramedullary
Malignant plasma cell tumour NOS
Plasmacytoma NOS
Solitary myeloma
#C90.3 Crow-Fukase / POEMS [polyneuropathy, organomegaly, endocrinopathy, M-protein and skin change] syndrome

C91 Lymphoid leukaemia
Includes: morphology codes M982, M9940-M9941 with behaviour code /3
C91.0 Acute lymphoblastic leukaemia
Excludes: acute exacerbation of chronic lymphocytic leukaemia ( C91.1 )
C91.1 Chronic lymphocytic leukaemia
C91.2 Subacute lymphocytic leukaemia
C91.3 Prolymphocytic leukaemia
C91.4 Hairy-cell leukaemia
Leukaemic reticuloendotheliosis
C91.5 Adult T-cell leukaemia
C91.7 Other lymphoid leukaemia
C91.9 Lymphoid leukaemia, unspecified

C92 Myeloid leukaemia
Includes: leukaemia:
· granulocytic
· myelogenous
morphology codes M986-M988, M9930 with behaviour code /3
C92.0 Acute myeloid leukaemia
Excludes: acute exacerbation of chronic myeloid leukaemia ( C92.1 )
C92.1 Chronic myeloid leukaemia
C92.2 Subacute myeloid leukaemia
C92.3 Myeloid sarcoma
Granulocytic sarcoma
C92.4 Acute promyelocytic leukaemia
C92.5 Acute myelomonocytic leukaemia
C92.7 Other myeloid leukaemia
C92.9 Myeloid leukaemia, unspecified

C93 Monocytic leukaemia
Includes: monocytoid leukaemia
morphology code M989 with behaviour code /3
C93.0 Acute monocytic leukaemia
Excludes: acute exacerbation of chronic monocytic leukaemia ( C93.1 )
C93.1 Chronic monocytic leukaemia
C93.2 Subacute monocytic leukaemia
C93.7 Other monocytic leukaemia
C93.9 Monocytic leukaemia, unspecified

C94 Other leukaemias of specified cell type
Includes: morphology codes M984, M9850, M9900, M9910, M9931-M9932 with behaviour code /3
Excludes: leukaemic reticuloendotheliosis ( C91.4 )
plasma cell leukaemia ( C90.1 )
C94.0 Acute erythraemia and erythroleukaemia
Acute erythraemic myelosis
Di Guglielmo's disease
C94.1 Chronic erythraemia
Heilmeyer-Schöner disease
C94.2 Acute megakaryoblastic leukaemia
· megakaryoblastic (acute)
· megakaryocytic (acute)
C94.3 Mast cell leukaemia
C94.4 Acute panmyelosis
C94.5 Acute myelofibrosis
C94.7 Other specified leukaemias
Lymphosarcoma cell leukaemia

C95 Leukaemia of unspecified cell type
Includes: morphology code M980 with behaviour code /3
C95.0 Acute leukaemia of unspecified cell type
Blast cell leukaemia
Stem cell leukaemia
Excludes: acute exacerbation of unspecified chronic leukaemia ( C95.1 )
C95.1 Chronic leukaemia of unspecified cell type
C95.2 Subacute leukaemia of unspecified cell type
C95.7 Other leukaemia of unspecified cell type
C95.9 Leukaemia, unspecified

C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
Includes: morphology codes M972, M974 with behaviour code /3
C96.0 Letterer-Siwe disease
· reticuloendotheliosis
· reticulosis
C96.1 Malignant histiocytosis
Histiocytic medullary reticulosis
C96.2 Malignant mast cell tumour
· mastocytoma
· mastocytosis
Mast cell sarcoma
Excludes: mast cell leukaemia ( C94.3 )
mastocytosis (cutaneous) ( Q82.2 )
C96.3 True histiocytic lymphoma
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
C96.9 Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified