This chapter contains the following broad groups of neoplasms:
|C00-C75||Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, haematopoietic and related tissue|
|C00-C14||Lip, oral cavity and pharynx|
|C30-C39||Respiratory and intrathoracic organs|
|C40-C41||Bone and articular cartilage|
|C45-C49||Mesothelial and soft tissue|
|C51-C58||Female genital organs|
|C60-C63||Male genital organs|
|C69-C72||Eye, brain and other parts of central nervous system|
|C73-C75||Thyroid and other endocrine glands|
|C76-C80||Malignant neoplasms of ill-defined, secondary and unspecified sites|
|C81-C96||Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue|
|C97||Malignant neoplasms of independent (primary) multiple sites|
|D00-D09||In situ neoplasms|
|D37-D48||Neoplasms of uncertain or unknown behaviour [see note before D37]|
In Chapter II neoplasms are classified predominantly by site within broad groupings for behaviour. In a few exceptional cases morphology is indicated in the category and subcategory titles.
For those wishing to identify the histological type of neoplasm, comprehensive separate morphology codes are provided ( see section Morphology of neoplasms). These morphology codes are derived from the second edition of International Classification of Diseases for Oncology (ICD-O), which is a dual-axis classification providing independent coding systems for topography and morphology. Morphology codes have six digits: the first four digits identify the histological type; the fifth digit is the behaviour code (malignant primary, malignant secondary (metastatic), in situ, benign, uncertain whether malignant or benign); and the sixth digit is a grading code (differentiation) for solid tumours, and is also used as a special code for lymphomas and leukaemias.
Sometimes a neoplasm overlaps the boundaries of three-character categories within certain systems. To take care of this the following subcategories have been designated:
C02.8 Overlapping lesion of tongue
An example of this is a carcinoma of the stomach and small intestine, which should be coded to C26.8 (Overlapping lesion of digestive system).
The introductory pages of Volume 3 include general instructions about the correct use of the Alphabetical Index. The specific instructions and examples pertaining to neoplasms should be consulted to ensure correct use of the categories and subcategories in Chapter II.
It is therefore recommended that agencies interested in identifying both the site and morphology of tumours, e.g. cancer registries, cancer hospitals, pathology departments and other agencies specializing in cancer, use ICD-O.